The ALTEC Mission Support Center provides engineering support to space shuttle missions who see the presence on board of the Logistics Modules MPLM or an Italian participation to it, at in the case of the Esperia Mission. Support is provided by an integrated team, consisting of engineers of ALTEC and Thales Alenia Space, which operates in the Mission Support Rooms of the CMFS. The Mission Support rooms are integrated into the international network at NASA and ESA Centers, enabling the operational management of the Space Station. During a mission our main objective is to offer support and assistance to ground personnel at control centers mainly during critical mission phases. We also perform engineering analysis in real-time and supply detailed information to the astronauts. The participation in the management of missions towards ISS offers ALTEC the unique opportunity to develop activities related to the promotion of space activities and the diffusion of knowledge throughout the area, on behalf of the space agencies.